2-Aminophenol → 2-(1-Methylpentylamino)phenol

HRID 1782554Notes

Reaction equation

HRID 1782554 reaction equation
[CH3:1][C:2](=[O:7])[CH2:3][CH2:4][CH2:5][CH3:6].[NH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1O>>[CH3:14][CH:9]([NH:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:1][C:2]=1[OH:7])[CH2:10][CH2:11][CH2:12][CH3:13]

Participants

3

Reactant 2

HCID 58012-AminophenolHCID 115832-Hexanone

Product 1

HCID 231068622-(1-Methylpentylamino)phenol

Procedure

The same procedure as in Example 3 was repeated except for using 145 mL (121 g; 1.2 mol) of 2-hexanone in place of 100 mL of acetone, to conduct the reaction. As a result, it was confirmed that the rate of conversion of o-aminophenol was 93%, the selectivity to the N-monoalkylated compound (molar ratio of the monoalkylated compound to a sum of the mono- and di-alkylated compounds) was 41%, and the oxygen absorption initiation time as an index of determining an oxidation-inhibiting property thereof was 320 min.

Workup

  1. customthe reaction
  2. customthe oxygen absorption initiation time as an index

Sources & evidence

ORD record
ord-15517788c82a494ab29657e4fdbb073d
Source dataset
uspto-grants-2009_03
Patent number
US07498467B2

Reaction notes

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