HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(1-Benzylpiperidin-4-yl)-1,3-dihydroimidazo[4,5-c]quinolin-2-one → 3-Piperidin-4-yl-1,3-dihydroimidazo[4,5-c]quinolin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(1-Benzylpiperidin-4-yl)-1,3-dihydroimidazo[4,5-c]quinolin-2-one | HCID 18321596 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 3-Piperidin-4-yl-1,3-dihydroimidazo[4,5-c]quinolin-2-one | HCID 18321559 | 98.5% |
Reaction Steps
Prepared analogously to Example A3f) from 1,3-dihydro-3-[1-(phenylmethyl)-4-piperidinyl]-2(2H)-imidazo[4,5-c]quinolone by hydrogenolysis in the presence of palladium/charcoal in a yield of 98.5% of theory. Colourless crystals, Rf=0.63 (FM1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07498325B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-30abbb25505948a5b8ad4e2f8ce04c26 |
| Source note | uspto-grants-2009_03 |