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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1782718Generated: October 30, 2026

Cyclohexanone → 1-(1,1-Dimethylethoxycarbonyl)-4-(1-cyclohexyl-4-piperidinyl)piperazine

https://huagongshe.com/reaction/1782718

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexanoneHCID 7967—
Reactanttert-Butyl 4-(piperidin-4-yl)piperazine-1-carboxylateHCID 17750356—
Product1-(1,1-Dimethylethoxycarbonyl)-4-(1-cyclohexyl-4-piperidinyl)piperazineHCID 1832108499%

Reaction Steps

Prepared analogously to Example A19a) from 1-(1,1-dimethyl-ethoxycarbonyl)-4-(4-piperidinyl)piperazine and cyclohexanone in a yield of 99% of theory. Colourless, highly viscous oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07498325B2
Source datasetuspto-grants-2009_03
ORD IDord-be8a991cb10f48eda9f0824b1e001707
Source noteuspto-grants-2009_03