1-Benzylpiperazine → HCID 18321263, compound

HRID 1782719Notes

Reaction equation

HRID 1782719 reaction equation
[CH2:1]([N:3]1[CH2:8][CH2:7][C:6](=O)[CH2:5][CH2:4]1)[CH3:2].[C:10]1([CH2:16][N:17]2[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]2)[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[CH2:1]([N:3]1[CH2:8][CH2:7][CH:6]([N:20]2[CH2:21][CH2:22][N:17]([CH2:16][C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=3)[CH2:18][CH2:19]2)[CH2:5][CH2:4]1)[CH3:2]

Participants

3

Reactant 2

HCID 759941-BenzylpiperazineHCID 771591-Ethylpiperidin-4-one

Product 1

HCID 18321263HCID 18321263, compoundYield 71%

Procedure

Prepared analogously to Example A19a) from 1-ethyl-4-piperidinone and 1-(phenylmethyl)piperazine in a yield of 71% of theory. Colourless, amorphous substance, Rf=0.46 (FM4).

Sources & evidence

ORD record
ord-f07c05b879ca4bf6b1bcdcb97110346b
Source dataset
uspto-grants-2009_03
Patent number
US07498325B2

Reaction notes

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