2-Hydroxy-5-(methoxycarbonyl)benzoic acid → HCID 57589141, compound

HRID 1782754Notes

Reaction equation

HRID 1782754 reaction equation
[OH:1][C:2]1[CH:10]=[CH:9][C:8]([C:11]([O:13][CH3:14])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=O.Cl.[NH:16]1[CH2:21][CH2:20][CH:19]([C:22]([O:24][CH3:25])=[O:23])[CH2:18][CH2:17]1>>[OH:1][C:2]1[CH:10]=[CH:9][C:8]([C:11]([O:13][CH3:14])=[O:12])=[CH:7][C:3]=1[C:4]([N:16]1[CH2:21][CH2:20][CH:19]([C:22]([O:24][CH3:25])=[O:23])[CH2:18][CH2:17]1)=[O:6]

Participants

3

Reactant 2

HCID 127170602-Hydroxy-5-(methoxycarbonyl)benzoic acidHCID 187838294-Piperidinecarboxylic acid, methyl ester, hydrochloride (1:1)

Product 1

HCID 57589141HCID 57589141, compound

Procedure

Methyl 1-[2-hydroxy-5-(methoxycarbonyl)benzoyl]-4-piperidinecarboxylate is prepared in analogy to the process described in Example IX, method 1, from 2-hydroxy-5-carbomethoxybenzoic acid [CAS No. 79128-78-2] and methyl piperidine-4-carboxylate hydrochloride.

Sources & evidence

ORD record
ord-5e6bafed4c4c4ef8ab93d67c01b0ad1a
Source dataset
uspto-grants-2009_03
Patent number
US07498460B2

Reaction notes

Loading…