5-(Methoxycarbonyl)-2-nitrobenzoic acid → HCID 57589175, compound

HRID 1782755Notes

Reaction equation

HRID 1782755 reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:6]=[CH:7][C:8]([N+:14]([O-:16])=[O:15])=[C:9]([CH:13]=1)[C:10]([OH:12])=O)=[O:4].Cl.[NH:18]1[CH2:23][CH2:22][CH:21]([C:24]([O:26][CH3:27])=[O:25])[CH2:20][CH2:19]1>>[CH3:1][O:2][C:3]([C:5]1[CH:6]=[CH:7][C:8]([N+:14]([O-:16])=[O:15])=[C:9]([CH:13]=1)[C:10]([N:18]1[CH2:23][CH2:22][CH:21]([C:24]([O:26][CH3:27])=[O:25])[CH2:20][CH2:19]1)=[O:12])=[O:4]

Participants

3

Reactant 2

HCID 149380985-(Methoxycarbonyl)-2-nitrobenzoic acidHCID 187838294-Piperidinecarboxylic acid, methyl ester, hydrochloride (1:1)

Product 1

HCID 57589175HCID 57589175, compound

Procedure

Methyl 1-[5-(methoxycarbonyl)-2-nitrobenzoyl]-4-piperidinecarboxylate is prepared in analogy to the process described in Example IX from 5-(methoxycarbonyl)-2-nitrobenzoic acid and methyl piperidine-4-carboxylate hydrochloride.

Sources & evidence

ORD record
ord-71d21d3c4714444f97f2936eaf326634
Source dataset
uspto-grants-2009_03
Patent number
US07498460B2

Reaction notes

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