HCID 57589070, compound → HCID 57589193, compound

HRID 1782767Notes

Reaction equation

HRID 1782767 reaction equation
Br[CH2:2][CH2:3][CH2:4][C:5]1[CH:21]=[CH:20][C:8]([O:9][Si:10]([CH:17]([CH3:19])[CH3:18])([CH:14]([CH3:16])[CH3:15])[CH:11]([CH3:13])[CH3:12])=[CH:7][CH:6]=1.[OH:22][C:23]1[CH:40]=[CH:39][C:38]([C:41]([O:43][CH3:44])=[O:42])=[CH:37][C:24]=1[C:25]([N:27]1[CH2:32][CH2:31][CH:30]([C:33]([O:35][CH3:36])=[O:34])[CH2:29][CH2:28]1)=[O:26]>>[CH3:44][O:43][C:41]([C:38]1[CH:39]=[CH:40][C:23]([O:22][CH2:2][CH2:3][CH2:4][C:5]2[CH:21]=[CH:20][C:8]([O:9][Si:10]([CH:17]([CH3:19])[CH3:18])([CH:14]([CH3:16])[CH3:15])[CH:11]([CH3:13])[CH3:12])=[CH:7][CH:6]=2)=[C:24]([CH:37]=1)[C:25]([N:27]1[CH2:28][CH2:29][CH:30]([C:33]([O:35][CH3:36])=[O:34])[CH2:31][CH2:32]1)=[O:26])=[O:42]

Participants

3

Reactant 2

HCID 57589070HCID 57589070, compoundHCID 57589141Methyl 1-[2-hydroxy-5-(methoxycarbonyl)benzoyl]-4-piperidinecarboxylate

Product 1

HCID 57589193HCID 57589193, compound

Procedure

Methyl 1-[5-(methoxycarbonyl)-2-(3-{4-[(triisopropylsilyl)oxy]phenyl}propoxy)-benzoyl]piperidine-4-carboxylate is prepared by the process described in Example XLI from [4-(3-bromopropyl)phenoxy](triisopropyl)silane and methyl 1-[2-hydroxy-5-(methoxycarbonyl)benzoyl]-4-piperidinecarboxylate.

Sources & evidence

ORD record
ord-4c0ada2053124579aa7f52ab98dd5765
Source dataset
uspto-grants-2009_03
Patent number
US07498460B2

Reaction notes

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