1-(3-Bromopropyl)-4-(4-phenoxybutoxy)benzene → HCID 57589081, compound

HRID 1782768Notes

Reaction equation

HRID 1782768 reaction equation
Br[CH2:2][CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][CH2:12][CH2:13][CH2:14][CH2:15][O:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:7][CH:6]=1.[OH:23][C:24]1[CH:41]=[CH:40][C:39]([C:42]([O:44][CH3:45])=[O:43])=[CH:38][C:25]=1[C:26]([N:28]1[CH2:33][CH2:32][CH:31]([C:34]([O:36][CH3:37])=[O:35])[CH2:30][CH2:29]1)=[O:27]>>[CH3:45][O:44][C:42]([C:39]1[CH:40]=[CH:41][C:24]([O:23][CH2:2][CH2:3][CH2:4][C:5]2[CH:10]=[CH:9][C:8]([O:11][CH2:12][CH2:13][CH2:14][CH2:15][O:16][C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[CH:7][CH:6]=2)=[C:25]([CH:38]=1)[C:26]([N:28]1[CH2:29][CH2:30][CH:31]([C:34]([O:36][CH3:37])=[O:35])[CH2:32][CH2:33]1)=[O:27])=[O:43]

Participants

3

Reactant 2

HCID 574437531-(3-Bromopropyl)-4-(4-phenoxybutoxy)benzeneHCID 57589141Methyl 1-[2-hydroxy-5-(methoxycarbonyl)benzoyl]-4-piperidinecarboxylate

Product 1

HCID 57589081HCID 57589081, compound

Procedure

Methyl 1-(5-(methoxycarbonyl)-2-{3-[4-(4-phenoxybutoxy)phenyl]propoxy}-benzoyl)-4-piperidinecarboxylate is prepared in analogy to the process described in Example 2 from 1-(3-bromopropyl)-4-(4-phenoxybutoxy)benzene and methyl 1-[2-hydroxy-5-(methoxycarbonyl)benzoyl]-4-piperidinecarboxylate.

Sources & evidence

ORD record
ord-b84c59f2dcf04e7f80bc6f293a54a439
Source dataset
uspto-grants-2009_03
Patent number
US07498460B2

Reaction notes

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