Methyl azetidine-3-carboxylate → Methyl 1-(5-(ethoxycarbonyl)-2-{3-[4-(4-phenoxybutoxy)phenyl]propoxy}benzoyl)-3-azetidinecarboxylate

HRID 1782771Notes

Reaction equation

HRID 1782771 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[CH:8][C:9]([O:15][CH2:16][CH2:17][CH2:18][C:19]2[CH:24]=[CH:23][C:22]([O:25][CH2:26][CH2:27][CH2:28][CH2:29][O:30][C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)=[CH:21][CH:20]=2)=[C:10]([CH:14]=1)[C:11](O)=[O:12])=[O:5])[CH3:2].[NH:37]1[CH2:40][CH:39]([C:41]([O:43][CH3:44])=[O:42])[CH2:38]1>>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[CH:8][C:9]([O:15][CH2:16][CH2:17][CH2:18][C:19]2[CH:20]=[CH:21][C:22]([O:25][CH2:26][CH2:27][CH2:28][CH2:29][O:30][C:31]3[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=3)=[CH:23][CH:24]=2)=[C:10]([CH:14]=1)[C:11]([N:37]1[CH2:40][CH:39]([C:41]([O:43][CH3:44])=[O:42])[CH2:38]1)=[O:12])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 20132751Methyl azetidine-3-carboxylateHCID 57589233HCID 57589233, compound

Product 1

HCID 57589054Methyl 1-(5-(ethoxycarbonyl)-2-{3-[4-(4-phenoxybutoxy)phenyl]propoxy}benzoyl)-3-azetidinecarboxylate

Procedure

The compound is prepared in analogy to the process described in Example 6 from 5-(ethoxycarbonyl)-2-{3-[4-(4-phenoxybutoxy)phenyl]propoxy}benzoic acid and methyl 3-azetidinecarboxylate [CAS No. 343238-58-4]. The crude product is immediately reacted further without purification.

Workup

  1. customThe compound is prepared in analogy to the process

Sources & evidence

ORD record
ord-7466348edf73467aa2ea84e6b996d0dc
Source dataset
uspto-grants-2009_03
Patent number
US07498460B2

Reaction notes

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