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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1782781Generated: November 1, 2026

1-(Chloromethyl)-4-phenoxybenzene → Methyl 3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)-4-(3-{4-[(4-phenoxybenzyl)oxy]phenyl}propoxy)benzoate

https://huagongshe.com/reaction/1782781

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Chloromethyl)-4-phenoxybenzeneHCID 520994—
ReactantMethyl 4-[3-(4-hydroxyphenyl)propoxy]-3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)benzoateHCID 57589128—
ProductMethyl 3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)-4-(3-{4-[(4-phenoxybenzyl)oxy]phenyl}propoxy)benzoateHCID 57589100—

Reaction Steps

Methyl 3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)-4-(3-{4-[(4-phenoxybenzyl)oxy]phenyl}propoxy)benzoate is prepared in analogy to the process described in Example 34 from methyl 4-[3-(4-hydroxyphenyl)propoxy]-3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)benzoate and 1-(chloromethyl)-4-phenoxybenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07498460B2
Source datasetuspto-grants-2009_03
ORD IDord-f7c7f55d484449249aa033c672f4fe67
Source noteuspto-grants-2009_03