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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1782782Generated: October 30, 2026

1-(chloromethyl)-4-isobutoxybenzene → Methyl 4-(3-{4-[(4-isobutoxybenzyl)oxy]phenyl}propoxy)-3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)benzoate

https://huagongshe.com/reaction/1782782

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(chloromethyl)-4-isobutoxybenzeneHCID 12249110—
ReactantHCID 57589128HCID 57589128—
ProductMethyl 4-(3-{4-[(4-isobutoxybenzyl)oxy]phenyl}propoxy)-3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)benzoateHCID 57589183—

Reaction Steps

Methyl 4-(3-{4-[(4-isobutoxybenzyl)oxy]phenyl}propoxy)-3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)benzoate is prepared in analogy to the process described in Example 34 from methyl 4-[3-(4-hydroxyphenyl)propoxy]-3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)benzoate and 1-(chloromethyl)-4-isobutoxybenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07498460B2
Source datasetuspto-grants-2009_03
ORD IDord-30761e5bf07a493e9f71192d55e3db2a
Source noteuspto-grants-2009_03