6-(Chloromethyl)-1,2,3,4-tetrahydronaphthalene → Methyl 3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)-4-{3-[4-(5,6,7,8-tetrahydronaphthalen-2-ylmethoxy)phenyl]propoxy}benzoate

Participants

Role	Name	HCID	Charge
Reactant	6-(Chloromethyl)-1,2,3,4-tetrahydronaphthalene	HCID 15562326	—
Reactant	HCID 57589128	HCID 57589128	—
Product	Methyl 3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)-4-{3-[4-(5,6,7,8-tetrahydronaphthalen-2-ylmethoxy)phenyl]propoxy}benzoate	HCID 57589094	—

Reaction Steps

Methyl 3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)-4-{3-[4-(5,6,7,8-tetrahydronaphthalen-2-ylmethoxy)phenyl]propoxy}benzoate is prepared in analogy to the process described in Example 34 from methyl 4-[3-(4-hydroxyphenyl)-propoxy]-3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)benzoate and 6-(chloromethyl)-1,2,3,4-tetrahydronaphthalene.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07498460B2
Source dataset	uspto-grants-2009_03
ORD ID	ord-8acc657d057242aabcab08b6c125f834
Source note	uspto-grants-2009_03