Methyl 1-[2-hydroxy-5-(methoxycarbonyl)benzoyl]-4-piperidinecarboxylate → HCID 57589208, compound

HRID 1782795Notes

Reaction equation

HRID 1782795 reaction equation
[OH:1][C:2]1[CH:19]=[CH:18][C:17]([C:20]([O:22][CH3:23])=[O:21])=[CH:16][C:3]=1[C:4]([N:6]1[CH2:11][CH2:10][CH:9]([C:12]([O:14][CH3:15])=[O:13])[CH2:8][CH2:7]1)=[O:5].Br[CH2:25][CH2:26][O:27][C:28]1[CH:47]=[CH:46][C:31]([O:32][CH2:33][C:34]2[CH:39]=[CH:38][C:37]([C:40]3[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=3)=[CH:36][CH:35]=2)=[CH:30][CH:29]=1>>[C:37]1([C:40]2[CH:41]=[CH:42][CH:43]=[CH:44][CH:45]=2)[CH:38]=[CH:39][C:34]([CH2:33][O:32][C:31]2[CH:46]=[CH:47][C:28]([O:27][CH2:26][CH2:25][O:1][C:2]3[CH:19]=[CH:18][C:17]([C:20]([O:22][CH3:23])=[O:21])=[CH:16][C:3]=3[C:4]([N:6]3[CH2:11][CH2:10][CH:9]([C:12]([O:14][CH3:15])=[O:13])[CH2:8][CH2:7]3)=[O:5])=[CH:29][CH:30]=2)=[CH:35][CH:36]=1

Participants

3

Reactant 2

HCID 57589141Methyl 1-[2-hydroxy-5-(methoxycarbonyl)benzoyl]-4-piperidinecarboxylateHCID 57589154HCID 57589154, compound

Product 1

HCID 57589208HCID 57589208, compound

Procedure

Preparation takes place in analogy to Example 22 from methyl 1-[2-hydroxy-5-(methoxycarbonyl)benzoyl]piperidine-4-carboxylate and 4-{[4-(2-bromoethoxy)-phenoxy]methyl}biphenyl.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-74a13dcdc6fc49508a80380110c24b62
Source dataset
uspto-grants-2009_03
Patent number
US07498460B2

Reaction notes

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