HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-hydroxy-3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)benzoate → Methyl 3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)-4-({3-[4-(4-phenoxy-butoxy)phenyl]prop-2-yn-1-yl}oxy)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-hydroxy-3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)benzoate | HCID 57589182 | — |
| Reactant | 1-(3-Bromoprop-1-yn-1-yl)-4-(4-phenoxy-butoxy)benzene | HCID 57589215 | — |
| Product | Methyl 3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)-4-({3-[4-(4-phenoxy-butoxy)phenyl]prop-2-yn-1-yl}oxy)benzoate | HCID 57589170 | — |
Reaction Steps
Preparation takes place in analogy to Example 22 from the (+)-B-enantiomer of methyl 4-hydroxy-3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)benzoate (see Example IX, method 2) and 1-(3-bromoprop-1-yn-1-yl)-4-(4-phenoxy-butoxy)benzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07498460B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-37c7b36e28f843359d9ba57c13f3bb80 |
| Source note | uspto-grants-2009_03 |