HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Bromopropyl)-4-[(4-phenoxybut-2-yn-1-yl)oxy]benzene → Methyl 3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)-4-(3-{4-[(4-phenoxy-but-2-yn-1-yl)oxy]phenyl}propoxy)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Bromopropyl)-4-[(4-phenoxybut-2-yn-1-yl)oxy]benzene | HCID 57589167 | — |
| Reactant | Methyl 4-hydroxy-3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)benzoate | HCID 57589182 | — |
| Product | Methyl 3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)-4-(3-{4-[(4-phenoxy-but-2-yn-1-yl)oxy]phenyl}propoxy)benzoate | HCID 57589025 | — |
Reaction Steps
Preparation takes place in analogy to Example 22 from the (+)-B-enantiomer of methyl 4-hydroxy-3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)benzoate (see Example IX, method 2) and 1-(3-bromopropyl)-4-[(4-phenoxybut-2-yn-1-yl)oxy]benzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07498460B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-0425a617dbda455a9d71e2939d534bc4 |
| Source note | uspto-grants-2009_03 |