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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1783219Generated: October 30, 2026

1-Aminotetralin, (S)- → HCID 69414983, compound

https://huagongshe.com/reaction/1783219

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Aminotetralin, (S)-HCID 7058074—
Reactanttert-Butyl ((S)-2-(3,5-difluorophenyl)-1-((S)-oxiran-2-yl)ethyl)carbamateHCID 9922319—
Reactant3-[(Dipropylamino)carbonyl]-5-Ethylbenzoic AcidHCID 22593642—
ProductHCID 69414983HCID 69414983—

Reaction Steps

Following the general procedure of EXAMPLEs 4, 5 and 6 and making non-critical variations but using tert-butyl (1S)-2-(3,5-difluorophenyl)-1-[(2S)-oxiranyl]ethylcarbamate (V, EXAMPLE 3), (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine (VI) and “5-Me-PHTH” (IX), the title compound is obtained, MH+=592.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07498436B2
Source datasetuspto-grants-2009_03
ORD IDord-14c4dce51e44407a900d4682dec68dd1
Source noteuspto-grants-2009_03