HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Fluoro-4-methoxyphenyl)methanol → 4-chloro-N-((R)-5,5-difluoro-2-oxo-azepan-3-yl)-N-(2-fluoro-4-methoxy-benzyl)-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Fluoro-4-methoxyphenyl)methanol | HCID 593638 | — |
| Reactant | 4-Chloro-N-((R)-5,5-difluoro-2-oxo-azepan-3-yl)-benzenesulfonamide | HCID 57589901 | — |
| Product | 4-chloro-N-((R)-5,5-difluoro-2-oxo-azepan-3-yl)-N-(2-fluoro-4-methoxy-benzyl)-benzenesulfonamide | HCID 44455804 | — |
Reaction Steps
4-Chloro-N-((R)-5,5-difluoro-2-oxo-azepan-3-yl)-benzenesulfonamide was reacted with (2-fluoro-4-methoxy-phenyl)-methanol analogous to Example 3a to afford 4-chloro-N-((R)-5,5-difluoro-2-oxo-azepan-3-yl)-N-(2-fluoro-4-methoxy-benzyl)-benzenesulfonamide:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07501406B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-c9479442081a4abe8b88415a5b1ed629 |
| Source note | uspto-grants-2009_03 |