HRID1783401

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2733581

1-(Bromomethyl)-4-methanesulfonylbenzene

C8H9BrO2S

结构：O=C1NCCC(F)(F)C[C@H]1NS(=O)(=O)c1ccc(Cl)cc1

HCID57589901

未命名化合物

PRODUCTS

生成物

结构：CS(=O)(=O)c1ccc(CN([C@@H]2CC(F)(F)CCNC2=O)S(=O)(=O)c2ccc(Cl)cc2)cc1

HCID68623426

未命名化合物

PROCEDURE

实验过程

4-Chloro-N-((R)-5,5-difluoro-2-oxo-azepan-3-yl)-benzenesulfonamide was alkylated using 4-methylsulphonylbenzyl bromide analogous to Example 1 to afford 4-chloro-N-((R)-5,5-difluoro-2-oxo-azepan-3-yl)-N-(4-methanesulfonylbenzyl)-benzenesulfonamide: MS: m/e=507.2 (MH+), 524.1(MNH4+).