HRID1783402

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2737001

4-(Difluoromethoxy)benzyl bromide

C8H7BrF2O

结构：O=C1NCCC(F)(F)C[C@H]1NS(=O)(=O)c1ccc(Cl)cc1

HCID57589901

未命名化合物

PRODUCTS

生成物

结构：O=C1NCCC(F)(F)C[C@H]1N(Cc1ccc(OC(F)F)cc1)S(=O)(=O)c1ccc(Cl)cc1

HCID68623657

未命名化合物

PROCEDURE

实验过程

4-Chloro-N-((R)-5,5-difluoro-2-oxo-azepan-3-yl)-benzenesulfonamide was alkylated using 4-(difluoromethoxy)benzyl bromide analogous to Example 1 to afford 4-chloro-N-(4-difluoromethoxy-benzyl)-N-((R)-5,5-difluoro-2-oxo-azepan-3-yl)-benzenesulfonamide: