HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(tert-Butoxycarbonyl)-4-((p-toluenesulfonyloxy)methyl)piperidine → HCID 68624965, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(tert-Butoxycarbonyl)-4-((p-toluenesulfonyloxy)methyl)piperidine | HCID 10642851 | — |
| Reactant | 4-Chloro-N-((R)-5,5-difluoro-2-oxo-azepan-3-yl)-benzenesulfonamide | HCID 57589901 | — |
| Product | HCID 68624965 | HCID 68624965 | — |
Reaction Steps
4-Chloro-N-((R)-5,5-difluoro-2-oxo-azepan-3-yl)-benzenesulfonamide was alkylated using 4-(toluene-4-sulfonyloxymethyl)-piperidine-1-carboxylic acid tert-butyl ester analogous to Example 1 to afford 4-{[(4-chloro-benzenesulfonyl)-((R)-5,5-difluoro-2-oxo-azepan-3-yl)-amino]-methyl}-piperidine-1-carboxylic acid tert-butyl ester:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07501406B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-e9ec1de09acc45cbb7a8c4c2532e7033 |
| Source note | uspto-grants-2009_03 |