HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Pyridin-3-yl-pyrimidin-2-ylamino)-benzoic acid ethyl ester → 4-(4-Thiazol-2-yl-pyrimidin-2-ylamino)-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Pyridin-3-yl-pyrimidin-2-ylamino)-benzoic acid ethyl ester | HCID 14346969 | — |
| Reactant | 4-(4-Thiazol-2-yl-pyrimidin-2-ylamino)-benzoic acid ethyl ester | HCID 68850816 | — |
| Product | 4-(4-Thiazol-2-yl-pyrimidin-2-ylamino)-benzoic acid | HCID 68850264 | — |
Reaction Steps
4-(4-thiazol-2-yl-pyrimidin-2-ylamino)-benzoic acid ethyl ester prepared in Preparation 9 was used instead of 4-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzoic acid ethyl ester according to the similar procedure to Preparation 19 to give the titled compound as yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07501424B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-1f5c71da940c4f679c6f2c868399b31d |
| Source note | uspto-grants-2009_03 |