4-(4-Pyridin-3-yl-pyrimidin-2-ylamino)-benzoic acid ethyl ester → HCID 68850820, compound

HRID 1783457Notes

Reaction equation

HRID 1783457 reaction equation
C([O:3][C:4](=[O:24])[C:5]1[CH:10]=[CH:9][C:8]([NH:11][C:12]2[N:17]=[C:16]([C:18]3[CH:23]=[N:22][CH:21]=[CH:20][N:19]=3)[CH:15]=[CH:14][N:13]=2)=[CH:7][CH:6]=1)C.C(OC(=O)C1C=CC(NC2N=C(C3C=NC=CC=3)C=CN=2)=CC=1)C>>[N:19]1[CH:20]=[CH:21][N:22]=[CH:23][C:18]=1[C:16]1[CH:15]=[CH:14][N:13]=[C:12]([NH:11][C:8]2[CH:7]=[CH:6][C:5]([C:4]([OH:24])=[O:3])=[CH:10][CH:9]=2)[N:17]=1

Participants

3

Reactant 2

HCID 143469694-(4-Pyridin-3-yl-pyrimidin-2-ylamino)-benzoic acid ethyl esterHCID 68849891HCID 68849891, compound

Product 1

HCID 68850820HCID 68850820, compound

Procedure

4-(4-pyrazin-2-yl-pyrimidin-2-ylamino)-benzoic acid ethyl ester prepared in Preparation 12 was used instead of 4-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzoic acid ethyl ester according to the similar procedure to Preparation 19 to give the titled compound as yellow solid.

Sources & evidence

ORD record
ord-df29148af2df4c8f8dc6666d914c9252
Source dataset
uspto-grants-2009_03
Patent number
US07501424B2

Reaction notes

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