HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1783497Generated: October 30, 2026
Potassium Carbonate → HCID 68905931, compound
https://huagongshe.com/reaction/1783497
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-Naphthalenethiol | HCID 68259 | — |
| Reactant | HCID 68834936 | HCID 68834936 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 68905931 | HCID 68905931 | — |
Reaction Steps
A mixture of 4-(6-iodobenzothiazol-2-yl)piperazine-1-carboxylic acid benzyl ester (0.370 g, 0.77 mmol), 1-napthalenethiol (0.124 g, 0.77 mmol), CuI (0.015 g, 0.08 mmol), and K2CO3 (0.213 g, 0.77 mmol) in isopropanol was heated at 90° C. overnight, cooled to 25° C., diluted with 20% MeOH in CH2Cl2, and filtered through a pad of silica gel. The filtrate was concentrated in vacuo to provide the title compound which used in Example 41 without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07501421B2 |
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| Source dataset | uspto-grants-2009_03 |
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| ORD ID | ord-0e0b81e8b38c4a44917d8ddedd10f6bd |
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| Source note | uspto-grants-2009_03 |
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