1,4-Dioxane → (4-Benzenesulphonyl-phenyl)-(6-(5-(1,3-dioxolan-2-yl)-furan-2-yl)-pyrido[3,4-d]pyrimidin-4-yl)-amine

HRID 178354Notes

Reaction equation

HRID 178354 reaction equation
[O:28]1[CH:29]([c:33]2[cH:34][cH:35][c:36]([Sn:38]([CH2:39][CH2:40][CH2:41][CH3:42])([CH2:43][CH2:44][CH2:45][CH3:46])[CH2:47][CH2:48][CH2:49][CH3:50])[o:37]2)[O:30][CH2:31][CH2:32]1.[O:51]1[CH2:52][CH2:53][O:54][CH2:55][CH2:56]1.[c:1]1([S:7](=[O:8])(=[O:9])[c:10]2[cH:11][cH:12][c:13]([NH:16][c:17]3[c:18]4[c:19]([n:20][cH:21][n:22]3)[cH:23][n:24][c:25]([Cl:27])[cH:26]4)[cH:14][cH:15]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([S:7](=[O:8])(=[O:9])[c:10]2[cH:11][cH:12][c:13]([NH:16][c:17]3[c:18]4[c:19]([n:20][cH:21][n:22]3)[cH:23][n:24][c:25](-[c:36]3[cH:35][cH:34][c:33]([CH:29]5[O:28][CH2:32][CH2:31][O:30]5)[o:37]3)[cH:26]4)[cH:14][cH:15]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

4

Reactant 3

HCID 312751,4-DioxaneHCID 10960952Stannane, tributyl[5-(1,3-dioxolan-2-yl)-2-furanyl]-HCID 219521656-Chloro-4-(4-phenylsulphonylanilino)pyrido[3,4-d]pyrimidine

Product 1

HCID 21952020(4-Benzenesulphonyl-phenyl)-(6-(5-(1,3-dioxolan-2-yl)-furan-2-yl)-pyrido[3,4-d]pyrimidin-4-yl)-amine

Sources & evidence

ORD record
ord-e73f4b6dfefb47ddbbcd8db41485ae0d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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