HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzoyl-3-methylpiperazine → 1-[(2R)-4-benzoyl-2-methyl-piperazin-1-yl]-2-[7-(4-methoxyphenyl)-1H-pyrrolo[3,2-b]pyridin-3-yl]ethane-1,2-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzoyl-3-methylpiperazine | HCID 10726887 | — |
| Reactant | Potassium 7-(4-methoxyphenyl)-4-azaindole-3-glyoxylate | HCID 59693981 | — |
| Product | 1-[(2R)-4-benzoyl-2-methyl-piperazin-1-yl]-2-[7-(4-methoxyphenyl)-1H-pyrrolo[3,2-b]pyridin-3-yl]ethane-1,2-dione | HCID 5280226 | — |
Reaction Steps
Example 67, 1-benzoyl-3-(R)-methyl-4-[(7-(4-methoxyphenyl)-4-azaindol-3-yl)oxoacetyl]piperazine was prepared from potassium 7-(4-methoxyphenyl)-4-azaindole-3-glyoxylate and the corresponding 1-benzoyl-3-methylpiperazine according to the above general procedure. MS m/z: (M+H)+ Calc'd for C28H27N4O4: 483.20; found 483.16. HPLC retention time: 1.28 minutes (column A).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07501420B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-a22c84f01d9f4f098ff42a4c46a8d78f |
| Source note | uspto-grants-2009_03 |