HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → Acetamide, N-(4-fluoro-3-nitrophenyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 4-Fluoro-3-nitroaniline | HCID 67768 | — |
| Product | Acetamide, N-(4-fluoro-3-nitrophenyl)- | HCID 67694 | 70% |
Reaction Steps
4-Fluoro-3-nitro-aniline (45.0 g, 288.2 mmol) was added portionwise to acetic anhydride (150 mL) at room temperature. The reaction mixture was stirred at room temperature for 2 h. The white solid was collected and dried in vacuo to give the desired title compound (42.0 g, 70%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07501447B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-e930e5e86d4642739fcf31be87fc626e |
| Source note | uspto-grants-2009_03 |