反应详情

温度

130 °C

In a round-bottom flask, a mixture of 2-cyclopropylamino-5-nitrobenzenesulphonamide (5 g), originating from the Step above, and ethyl orthoformate (50 mL) is heated in the open state at 130° C. for 3 hours. The suspension obtained is cooled on an ice bath and the insoluble material is collected by filtration, washed with ether and dried.

1. customThe suspension obtained
2. temperatureis cooled on an ice bath
3. filtrationthe insoluble material is collected by filtration
4. washwashed with ether
5. customdried