HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzo[b]thiophene-3-boronic acid pinacol ester → (5-Benzo[b]thiophen-3-yl-[1,2,4]triazolo[1,5-a]pyrazin-8-yl)-(4-morpholin-4-ylphenyl)amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzo[b]thiophene-3-boronic acid pinacol ester | HCID 10658979 | — |
| Reactant | (5-Bromo-[1,2,4]triazolo[1,5-a]pyrazin-8-yl)-(4-morpholin-4-ylphenyl)amine | HCID 57589931 | — |
| Product | (5-Benzo[b]thiophen-3-yl-[1,2,4]triazolo[1,5-a]pyrazin-8-yl)-(4-morpholin-4-ylphenyl)amine | HCID 24888779 | — |
Reaction Steps
This compound may be prepared using methods as described for Compound 120, using (5-bromo-[1,2,4]triazolo[1,5-a]pyrazin-8-yl)-(4-morpholin-4-ylphenyl)amine and 4,4,5,5-tetramethyl-2-benzo[b]thiophen-3-yl-[1,3,2]dioxaborolane in step 4. LCMS: Rt 0.84 min (95%), m/z (ESI) 402 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07501411B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-a066fb1722274b7c9b1147bd17cfb52b |
| Source note | uspto-grants-2009_03 |