HCID 66882720, compound → HCID 66881155, compound

Participants

Reaction Steps

The crude material 1b (13.7 g) was dissolved in 200 ml of MeOH and 20 ml of 7 N NaOH, the solution was stirred at 22° C. for 2 h and evaporated. The residue was partitioned between 0.1 N NaOH and CH2Cl2, the aqueous layer was washed with CH2Cl2 and the aqueous layer was acidified with 25% HCl, the suspension was filtered and the residue dried to give 11.0 g (45% overall) of the pure title compound 1c as a pale brown solid. MS: 278.3 (M−H)−.

Provenance & Evidence