HCID 18453166, compound → HCID 66882678, compound

HRID 1784037Notes

Reaction equation

HRID 1784037 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([CH:11]2[CH2:15][C:14](=[CH2:16])[CH2:13][CH:12]2[NH2:17])=[O:10])=[CH:4][CH:3]=1.[F:18][C:19]1[CH:27]=[C:26]([N:28]2[CH:33]=[CH:32][CH:31]=[CH:30][C:29]2=[O:34])[CH:25]=[CH:24][C:20]=1[C:21](O)=[O:22]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([CH:11]2[CH2:15][C:14](=[CH2:16])[CH2:13][CH:12]2[NH:17][C:21](=[O:22])[C:20]2[CH:24]=[CH:25][C:26]([N:28]3[CH:33]=[CH:32][CH:31]=[CH:30][C:29]3=[O:34])=[CH:27][C:19]=2[F:18])=[O:10])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 18453166HCID 18453166, compoundHCID 66882987HCID 66882987, compound

Product 1

HCID 66882678HCID 66882678, compoundYield 69%

Procedure

Starting from 35d and 35e, the title compound was prepared in 69% yield according to the procedure for example 1 and 2, step 2. MS: 466.3 (M+H)+.

Sources & evidence

ORD record
ord-a1cc029d64cf4cc0906cc80cbeb6081b
Source dataset
uspto-grants-2009_03
Patent number
US07501413B2

Reaction notes

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