Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-m-cresol → 2-(2-Hydroxy-6-methyl-phenylamino)-9-methoxy-6,7-dihydro-pyrimido[6,1-a]isoquinolin-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-m-cresol | HCID 3014138 | — |
| 반응물 | 2-chloro-9-methoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one | HCID 57591093 | — |
| 생성물 | 2-(2-Hydroxy-6-methyl-phenylamino)-9-methoxy-6,7-dihydro-pyrimido[6,1-a]isoquinolin-4-one | HCID 57591097 | — |
반응 단계
The title compound was prepared from 2-chloro-9-methoxy-6,7-dihydro-pyrimido[6,1-a]isoquinolin-4-one (4) and 2-hydroxy-6-methyl-aniline as in Example 1 d. 1H-NMR (400 MHz, d6-DMSO, at 60° C.) δ 9.39 (br, 1H), 8.60 (br, 1H), 7.61 (br, 1H), 7.05-6.95 (3H), 6.75 (d, 1H), 6.73 (d, 1H), 6.34 (br, 1H), 3.95 (t, 2H), 3.83 (s, 3H), 2.95 (t, 2H), and 2.19 (s, 3H); MS (ESI) (M+H)+ 350.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07501512B2 |
| 출처 데이터셋 | uspto-grants-2009_03 |
| ORD ID | ord-1213ad2a0e2b4298960163ed0da23b17 |
| 출처 메모 | uspto-grants-2009_03 |