HCID 178508812, compound → HCID 178508811, compound

HRID 1784111Notes

Reaction equation

HRID 1784111 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([OH:8])[C:5]([N:9]=O)=[C:4]([NH2:11])[N:3]=1>[NH4+]=S>[NH2:1][C:2]1[N:7]=[C:6]([OH:8])[C:5]([NH2:9])=[C:4]([NH2:11])[N:3]=1

Participants

2

Reactant 1

HCID 178508812HCID 178508812, compound

Product 1

HCID 178508811HCID 178508811, compoundYield 83%

Conditions

Temperature
50 °C

Procedure

A suspension of the compound of example 46 (15 g, 96.7 mmoles) in an ammonium sulfide solution (20% in water, 200 ml) was stirred overnight at 50° C. The reaction mixture was cooled down in the refrigerator and the precipitate was filtered off, providing the title compound as a yellow powder (11.33 g, yield: 83%). The spectral data are identical with literature data (Landauer et al. cited supra).

Workup

  1. temperatureThe reaction mixture was cooled down in the refrigerator
  2. filtrationthe precipitate was filtered off

Sources & evidence

ORD record
ord-f987076083aa44828852f22275108aee
Source dataset
uspto-grants-2009_03
Patent number
US07501513B2

Reaction notes

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