HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-bromobenzoic acid → (2S)-(2-amino-5-bromo-benzoyl-amino)-3-biphenyl-4-yl-propionic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-bromobenzoic acid | HCID 79858 | — |
| Reactant | (S)-Methyl 3-([1,1'-biphenyl]-4-yl)-2-aminopropanoate | HCID 15714801 | — |
| Product | (2S)-(2-amino-5-bromo-benzoyl-amino)-3-biphenyl-4-yl-propionic acid methyl ester | HCID 68860272 | 82.3% |
Reaction Steps
(2S)-(2-amino-5-bromo-benzoyl-amino)-3-biphenyl-4-yl-propionic acid methyl ester (1.53 g, 80%) was prepared from (2S)-amino-3-biphenyl-4-yl-propionic acid methyl ester (1.0 g, 4.1 mmol) and 5-bromo-2-amino-benzoic acid (1.23 g, 4.9 mmol) as described in procedure A.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07501538B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-4a15a491c355436d97368bb672ec079a |
| Source note | uspto-grants-2009_03 |