2-Bromo-5-methylpyridine → HCID 23120568, compound

HRID 1784739Notes

Reaction equation

HRID 1784739 reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:10]=[CH:9][C:8](B(O)O)=[CH:7][CH:6]=1)=[O:4].Br[C:15]1[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][N:16]=1>>[CH3:21][C:18]1[CH:19]=[CH:20][C:15]([C:8]2[CH:9]=[CH:10][C:5]([C:3]([O:2][CH3:1])=[O:4])=[CH:6][CH:7]=2)=[N:16][CH:17]=1

Participants

3

Reactant 2

HCID 5642162-Bromo-5-methylpyridineHCID 27343694-Methoxycarbonylphenylboronic acid

Product 1

HCID 23120568HCID 23120568, compound

Procedure

Repeating the operations of Production Example 14 using 4-(methoxycarbonyl)phenylboronic acid and 2-bromo-5-methylpyridine, methyl 4-(5-methyl-2-pyridyl)benzoate was obtained. Hydrolyzing the same with 5N aqueous sodium hydroxide solution, the title compound was obtained as white solid.

Sources & evidence

ORD record
ord-219a172ed1f541e9964bc63f0fbf5490
Source dataset
uspto-grants-2009_03
Patent number
US07504412B2

Reaction notes

Loading…