2,5-Dichloropyridine → HCID 22730477, compound

HRID 1784740Notes

Reaction equation

HRID 1784740 reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:10]=[CH:9][C:8](B(O)O)=[CH:7][CH:6]=1)=[O:4].Cl[C:15]1[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][N:16]=1>>[Cl:21][C:18]1[CH:19]=[CH:20][C:15]([C:8]2[CH:9]=[CH:10][C:5]([C:3]([O:2][CH3:1])=[O:4])=[CH:6][CH:7]=2)=[N:16][CH:17]=1

Participants

3

Reactant 2

HCID 276852,5-DichloropyridineHCID 27343694-Methoxycarbonylphenylboronic acid

Product 1

HCID 22730477HCID 22730477, compound

Procedure

Repeating the operations of Production Example 14 using 4-(methoxycarbonyl)phenylboronic acid and 2,5-dichloropyridine, methyl 4-(5-chloro-2-pyridyl)benzoate was obtained. Hydrolyzing the same with 5N aqueous sodium hydroxide solution, the title compound was obtained as white solid.

Sources & evidence

ORD record
ord-aa062152557a40419e3d9d16e682ccd0
Source dataset
uspto-grants-2009_03
Patent number
US07504412B2

Reaction notes

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