4-Carboxyphenylboronic Acid → HCID 23120528, compound

HRID 1784742Notes

Reaction equation

HRID 1784742 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][C:7](B(O)O)=[CH:6][CH:5]=1)([OH:3])=[O:2].Br[C:14]1[CH:15]=[CH:16][C:17]([CH:20]([F:22])[F:21])=[N:18][CH:19]=1>>[F:21][CH:20]([F:22])[C:17]1[N:18]=[CH:19][C:14]([C:7]2[CH:8]=[CH:9][C:4]([C:1]([OH:3])=[O:2])=[CH:5][CH:6]=2)=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 3121834-Carboxyphenylboronic AcidHCID 534150625-Bromo-2-(difluoromethyl)pyridine

Product 1

HCID 23120528HCID 23120528, compound

Procedure

Operations similar to those of Production Example 14 were conducted using 4-carboxyphenylboronic acid and 5-bromo-2-(difluoromethyl)pyridine, to provide the title compound as white solid.

Sources & evidence

ORD record
ord-813bc511fa8c488fbc2de6d165096ca0
Source dataset
uspto-grants-2009_03
Patent number
US07504412B2

Reaction notes

Loading…