4-Fluorophenylboronic acid → HCID 20567008, compound

HRID 1784746Notes

Reaction equation

HRID 1784746 reaction equation
[NH2:1][C:2]1[CH:7]=[N:6][C:5](Br)=[CH:4][N:3]=1.[F:9][C:10]1[CH:15]=[CH:14][C:13](B(O)O)=[CH:12][CH:11]=1>>[NH2:1][C:2]1[CH:7]=[N:6][C:5]([C:13]2[CH:14]=[CH:15][C:10]([F:9])=[CH:11][CH:12]=2)=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 2856454-Fluorophenylboronic acidHCID 5995392-Amino-5-bromopyrazine

Product 1

HCID 20567008HCID 20567008, compound

Procedure

Conducting the operations similar to those of Production Example 14 using 2-amino-5-bromopyrazine (2.7 g) and 4-fluorophenylboronic acid (3.4 g), 2-amino-5-(4-fluorophenyl)pyrazine was obtained as white solid.

Sources & evidence

ORD record
ord-e4c9e6e11d9449da9308875330f71e1e
Source dataset
uspto-grants-2009_03
Patent number
US07504412B2

Reaction notes

Loading…