4-(4-Fluorophenyl)benzoic acid → HCID 23120569, compound

HRID 1784751Notes

Reaction equation

HRID 1784751 reaction equation
Br.[CH:2]([C:5]1[N:6]=[C:7]2[CH:12]=[CH:11][C:10]([N+:13]([O-])=O)=[CH:9][N:8]2[CH:16]=1)([CH3:4])[CH3:3].[F:17][C:18]1[CH:23]=[CH:22][C:21]([C:24]2[CH:29]=[CH:28][C:27]([C:30](O)=[O:31])=[CH:26][CH:25]=2)=[CH:20][CH:19]=1>>[F:17][C:18]1[CH:19]=[CH:20][C:21]([C:24]2[CH:29]=[CH:28][C:27]([C:30]([NH:13][C:10]3[CH:11]=[CH:12][C:7]4[N:8]([CH:16]=[C:5]([CH:2]([CH3:4])[CH3:3])[N:6]=4)[CH:9]=3)=[O:31])=[CH:26][CH:25]=2)=[CH:22][CH:23]=1

Participants

3

Reactant 2

HCID 27826894-(4-Fluorophenyl)benzoic acidHCID 23120553HCID 23120553, compound

Product 1

HCID 23120569HCID 23120569, compound

Procedure

Conducting the operations similar to those of Example 1 using 2-isopropyl-6-nitroimidazo[1,2-a]pyridine hydrobromide and 4′-fluoro[1,1′-biphenyl]-4-carboxylic acid, the title compound was obtained as white solid.

Sources & evidence

ORD record
ord-d377743f8c224d618db6e7cc8d9e42ca
Source dataset
uspto-grants-2009_03
Patent number
US07504412B2

Reaction notes

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