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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1784753Generated: November 1, 2026

4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid → N-(3-methylimidazo[1,2-a]pyridin-6-yl)-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxamide

https://huagongshe.com/reaction/1784753

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acidHCID 2782719—
Reactant3-Methyl-6-nitroimidazo[1,2-a]pyridineHCID 21827346—
ProductN-(3-methylimidazo[1,2-a]pyridin-6-yl)-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxamideHCID 57594110—

Reaction Steps

Conducting the operations similar to those of Example 1 using 3-methyl-6-nitroimidazo[1,2-a]pyridine and 4′-(trifluoromethyl)-[1,1′-biphenyl]-4-carboxylic acid, the title compound was obtained as white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504412B2
Source datasetuspto-grants-2009_03
ORD IDord-aa58958213264d5881885ba6b7704af5
Source noteuspto-grants-2009_03