4-(6-Fluoropyridin-3-yl)benzoic acid → N-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-(6-fluoro-3-pyridyl)benzamide hydrochloride

Participants

Reaction Steps

Operations similar to those of Example 1 were conducted using 2-cyclopropyl-3-methyl-6-nitroimidazo[1,2-a]pyridine and 4-(6-fluoro-3-pyridyl)benzenecarboxylic acid. The resulting solid was dissolved in ethyl acetate, followed by addition of 4N hydrochloric acid-ethyl acetate solution and concentration under reduced pressure. The title compound was obtained as white solid.

Provenance & Evidence