4-[5-(Trifluoromethyl)pyridin-2-yl]benzoic acid → HCID 23120583, compound

HRID 1784765Notes

Reaction equation

HRID 1784765 reaction equation
[CH3:1][C:2]1[N:6]2[CH:7]=[C:8]([N+:11]([O-])=O)[CH:9]=[CH:10][C:5]2=[N:4][C:3]=1[CH:14]1[CH2:18][CH2:17][O:16][CH2:15]1.[F:19][C:20]([F:37])([F:36])[C:21]1[CH:22]=[CH:23][C:24]([C:27]2[CH:32]=[CH:31][C:30]([C:33](O)=[O:34])=[CH:29][CH:28]=2)=[N:25][CH:26]=1>>[CH3:1][C:2]1[N:6]2[CH:7]=[C:8]([NH:11][C:33](=[O:34])[C:30]3[CH:29]=[CH:28][C:27]([C:24]4[CH:23]=[CH:22][C:21]([C:20]([F:37])([F:19])[F:36])=[CH:26][N:25]=4)=[CH:32][CH:31]=3)[CH:9]=[CH:10][C:5]2=[N:4][C:3]=1[CH:14]1[CH2:18][CH2:17][O:16][CH2:15]1

Participants

3

Reactant 2

HCID 227306714-[5-(Trifluoromethyl)pyridin-2-yl]benzoic acidHCID 23120526HCID 23120526, compound

Product 1

HCID 23120583HCID 23120583, compound

Procedure

Conducting the operations similar to those of Example 1 using 3-methyl-6-nitro-2-tetrahydro-3-furanylimidazo[1,2-a]pyridine and 4-[5-(trifluoromethyl)-2-pyridyl]benzenecarboxylic acid, the title compound was obtained as white solid.

Sources & evidence

ORD record
ord-78f3a0969f734ff0bb0c3bcd6300676e
Source dataset
uspto-grants-2009_03
Patent number
US07504412B2

Reaction notes

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