2-Cyclopropyl-3-methyl-6-nitroimidazo[1,2-a]pyridine → HCID 23120522, compound

HRID 1784770Notes

Reaction equation

HRID 1784770 reaction equation
[CH:1]1([C:4]2[N:5]=[C:6]3[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[CH:8][N:7]3[C:15]=2[CH3:16])[CH2:3][CH2:2]1.[F:17][CH:18]([F:34])[C:19]1[N:24]=[CH:23][C:22]([C:25]2[CH:30]=[CH:29][C:28]([C:31](O)=[O:32])=[CH:27][CH:26]=2)=[CH:21][CH:20]=1>>[CH:1]1([C:4]2[N:5]=[C:6]3[CH:11]=[CH:10][C:9]([NH:12][C:31](=[O:32])[C:28]4[CH:29]=[CH:30][C:25]([C:22]5[CH:23]=[N:24][C:19]([CH:18]([F:34])[F:17])=[CH:20][CH:21]=5)=[CH:26][CH:27]=4)=[CH:8][N:7]3[C:15]=2[CH3:16])[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 231205162-Cyclopropyl-3-methyl-6-nitroimidazo[1,2-a]pyridineHCID 23120528HCID 23120528, compound

Product 1

HCID 23120522HCID 23120522, compound

Procedure

Conducting the operations similar to those of Example 1 using 2-cyclopropyl-3-methyl-6-nitroimidazo[1,2-a]pyridine and 4-[6-(difluoromethyl)-3-pyridyl]benzenecarboxylic acid, the title compound was obtained as white solid.

Sources & evidence

ORD record
ord-f1e9d625d2be4c0bb5d8523a66c12da0
Source dataset
uspto-grants-2009_03
Patent number
US07504412B2

Reaction notes

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