HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Fluoronitrobenzene → 4-(2-Carboxymethoxyphenoxy)nitrobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Fluoronitrobenzene | HCID 9590 | — |
| Reactant | (o-Hydroxyphenoxy)acetic acid | HCID 22783 | — |
| Reactant | potassium t-butoxide DMA | HCID 131726543 | — |
| Product | 4-(2-Carboxymethoxyphenoxy)nitrobenzene | HCID 22048504 | — |
Reaction Steps
4-(fluoro)nitrobenzene was reacted with 2-(2-hydroxyphenoxy)acetic acid in the presence of potassium t-butoxide/DMA at 150° C. for 2 hrs to give 2-[(2-(4-nitrophenoxy)phenoxy] acetic acid. The product was purified by chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07504416B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-7e59939bc5984fb29736b4935ff5f651 |
| Source note | uspto-grants-2009_03 |