HCID 52952226, compound → HCID 15602994, compound

Participants

Reaction Steps

N-[3-chloro-5-(pyridine-3-sulfonyl)-phenyl]-acetamide was converted to N-[3-(pyridine-3-sulfonyl)-5-(1-triisopropylsilanyl-1H-indol-4-yl)-phenyl]-acetamide and the triisopropylsilyl protecting group was removed as described in Example 35. 1H NMR (400 MHz, CD3OD): δ 9.17 (br s, 1H), 8.82 (br s, 1H), 8.38 (d, J=8.4 Hz, 1H), 8.30 (s, 1H), 8.12 (s, 1H), 7.96 (d, J=1.4 Hz, 1H), 7.63 (s, 1H), 7.44 (d, J=8.2 Hz, 1H), 7.31 (d, J=3.3 Hz, 1H), 7.19 (t, J=7.7 Hz, 1H), 7.10 (d, J=7.4 Hz, 1H), 6.53 (d, J=3.2 Hz, 1H), 2.15 (s, 3H).

Provenance & Evidence