HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitro-2-vinylpyridine → 2-Ethylpyridin-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitro-2-vinylpyridine | HCID 11829617 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethylacetate methanol | HCID 21584119 | — |
| Product | 2-Ethylpyridin-3-amine | HCID 21881800 | 89.1% |
Reaction Steps
To a solution of 0.220 g (1.47 mmol) of 3-nitro-2-vinyl-pyridine dissolved in 1:1 methanol/ethyl acetate was added 0.010 g of Pd/C. The resulting mixture was hydrogenated overnight at 50 psi. Filtration and removal of solvent provided 0.160 g (89% yield) of 2-ethyl-pyridin-3-ylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07504401B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-c6a65ec3dd0942a3b631b6ed572f7e46 |
| Source note | uspto-grants-2009_03 |