HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiophenol → N-{4-[2-Amino-3,5-dicyano-6-(phenylsulphanyl)-4-pyridinyl]phenyl}acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiophenol | HCID 7969 | — |
| Reactant | Malononitrile | HCID 8010 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | N-(4-(2,2-Dicyanoethenyl)phenyl)acetamide | HCID 33296 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-{4-[2-Amino-3,5-dicyano-6-(phenylsulphanyl)-4-pyridinyl]phenyl}acetamide | HCID 12016387 | — |
Reaction Steps
19 g (0.09 mol) of N-[4-(2,2-dicyanovinyl)phenyl]acetamide, 5.95 g (0.09 mol) of malononitrile and 9.91 g (0.09 mol) of thiophenol are initially charged in 120 ml of ethanol, and 0.4 ml of triethylamine are added. The mixture is stirred at reflux for 2 h, during which the product crystallizes. After cooling, the product is filtered off with suction and dried under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07504421B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-c08b117f2676448eb81e4c74ab745903 |
| Source note | uspto-grants-2009_03 |