反应详情

温度

0 °C

Dess-Martin periodinane (3 gm, 7.07 mmol) was added to (3-methoxy-4-methylphenyl)methanol (1 gm, 6.57 mmol) in CH2Cl2 (35 ml) at 0° C. After stirring at 0° C. for 0.5 h, some of the CH2Cl2 was removed, reaction mixture was diluted with ether, washed with sodium bicarbonate solution, sodium thiosulfate solution and water. Organic layer was dried and evaporated to obtain 3-methoxy-4-methylbenzaldehyde in quantitative yield.

1. customsome of the CH2Cl2 was removed
2. customreaction mixture
3. washwashed with sodium bicarbonate solution, sodium thiosulfate solution and water
4. customOrganic layer was dried
5. customevaporated