(3-Acetamidophenyl)boronic acid → HCID 57594941, compound

HRID 1785013Notes

Reaction equation

HRID 1785013 reaction equation
[CH2:1]([C:3]1[C:4]([C:11]([O:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[O:12])=[C:5]([CH:9]=[O:10])[NH:6][C:7]=1I)[CH3:2].FC1C=CC(B(O)O)=CC=1.[C:31]([NH:34][C:35]1[CH:36]=[C:37](B(O)O)[CH:38]=[CH:39][CH:40]=1)(=[O:33])[CH3:32]>>[C:31]([NH:34][C:35]1[CH:40]=[C:39]([C:7]2[NH:6][C:5]([CH:9]=[O:10])=[C:4]([C:11]([O:13][CH2:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[O:12])[C:3]=2[CH2:1][CH3:2])[CH:38]=[CH:37][CH:36]=1)(=[O:33])[CH3:32]

Participants

4

Reactant 3

HCID 157274(3-Acetamidophenyl)boronic acidHCID 2856454-Fluorophenylboronic acidHCID 11349592Benzyl 4-ethyl-2-formyl-5-iodo-1H-pyrrole-3-carboxylate

Product 1

HCID 57594941HCID 57594941, compound

Procedure

Following the procedures described in Example 5, replacing methyl 4-ethyl-2-formyl-5-iodo-1H-pyrrole-3-carboxylate with benzyl 4-ethyl-2-formyl-5-iodo-1H-pyrrole-3-carboxylate and 4-fluorophenylboronic acid with 3-(acetylamino) phenylboronic acid, the title compound was obtained. Proton NMR for the product was consistent with the title compound. HRMS (ES) exact mass calculated for C23H23N2O4 (M+H): 391.1653. Found 391.1651

Sources & evidence

ORD record
ord-54feba516f3c41c483dc887b65debd2c
Source dataset
uspto-grants-2009_03
Patent number
US07504429B2

Reaction notes

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