4-Fluorophenylboronic acid → HCID 11360490, compound

Participants

Reaction Steps

Following the procedures described in Example 5, replacing methyl 4-ethyl-2-formyl-5-iodo-1H-pyrrole-3-carboxylate with benzyl 4-ethyl-2-formyl-5-iodo-1H-pyrrole-3-carboxylate and 4-fluorophenylboronic acid with 3-methoxyphenylboronic acid, the title compound was obtained. Proton NMR for the product was consistent with the title compound. 1H NMR (500 MHz, CDCl3) δ 10.14 (s,.1H); 7.45 (m, 2H); 7.36-7.41 (m, 4H); 7.02 (m 2H); 6.96 (m, 2H); 5.39 (s, 2H); 3.85 (s, 3H); 2.85 (q, J=7.3 Hz, 2H); 1.21 (t, J=7.3 Hz, 3H). HRMS (ES) exact mass calculated for C22H22NO4 (M+H): 364.1594. Found 364.1573

Provenance & Evidence