Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785021Generated: October 29, 2026

4-Fluorophenylboronic acid → Benzyl 4-ethyl-2-formyl-5-(4-nitrophenyl)-1H-pyrrole-3-carboxylate

https://huagongshe.com/reaction/1785021

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorophenylboronic acidHCID 285645—
Reactant4-Nitrophenylboronic acidHCID 2773552—
ReactantBenzyl 4-ethyl-2-formyl-5-iodo-1H-pyrrole-3-carboxylateHCID 11349592—
ProductBenzyl 4-ethyl-2-formyl-5-(4-nitrophenyl)-1H-pyrrole-3-carboxylateHCID 11372360—

Reaction Steps

Following the procedures described in Example 5, replacing methyl 4-ethyl-2-formyl-5-iodo-1H-pyrrole-3-carboxylate with benzyl 4-ethyl-2-formyl-5-iodo-1H-pyrrole-3-carboxylate and 4-fluorophenylboronic acid with 4-nitrophenylboronic acid, the title compound was obtained. Proton NMR for the product was consistent with the title compound. HRMS (ES) exact mass calculated for C21H19N2O5 (M+H): 379.1216. Found 379.1270

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504429B2
Source datasetuspto-grants-2009_03
ORD IDord-00101ddf8ec64b46b714b3e291d73cd7
Source noteuspto-grants-2009_03